Sign Out
Symptoms and Signs: Gastrointestinal symptoms and disturbance of the fluid and electrolyte balances may be evident.
Amoxicillin crystalluria, in some cases leading to renal failure, has been observed (see Precautions).
Treatment: Gastrointestinal symptoms may be treated symptomatically, with attention to the water/electrolyte balance.
Co-amoxiclav can be removed from the circulation by haemodialysis.
Children (Additional Statement): A prospective study of 51 paediatric patients at a poison control centre suggested that overdosages of less than 250 mg/kg amoxicillin are not associated with significant clinical symptoms and do not require gastric emptying.
Augmentin: Drug Abuse and Dependence: Drug dependency, addiction and recreational abuse have not been reported as a problem with this compound.
